Hotel 21C
Lifestyle by Ennismore At the corner of curiosity
Hotel 21C

At the corner of curiosity

Contemporary Art Museum

21c Museum Hotels pushes the boundaries of both the museum and hotel worlds to create a new kind of travel experience. Founded as a single property by contemporary art collectors and preservationists Laura Lee Brown and Steve Wilson, whose mission was to share innovative contemporary art with the public. With locations ranging from 19th century warehouses to banks, 21c Museum Hotels create a union of genuine hospitality, thoughtful design, and culinary creativity — all anchored by a contemporary art museum.

Take me to 21c

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Our hotels selection

  • 21c Museum Hotel Louisville

    Nestled in downtown Louisville on historic West Main Street, along Museum Row, 21c Museum Hotel Louisville - MGallery is a multi-venue contemporary art museum, an award-winning 91-room boutique hotel, and home to acclaimed Proof on Main restaurant, led by executive chef Jonathan Searle. Stay with us and the iconic Red Penguin.

  • 21c Museum Hotel Cincinnati

    Situated in the heart of The Queen City, adjacent to the Contemporary Art Center and across the street from the Aronoff Center for the Arts, 21c Museum Hotel Cincinnati- MGallery is a multi-venue contemporary art museum, an award-winning 156-room boutique hotel and home of Metropole restaurant. Stay with us and the iconic Yellow Penguin.

  • 21c Museum Hotel Bentonville

    Located on the northeast corner of the Bentonville town square and a short walk to Crystal Bridges Museum of American Art, 21c Museum Hotel Bentonville - MGALLERY is a 104-room boutique hotel, contemporary art museum, cultural center and home to The Hiverestaurant, led by executive chef Matthew McClure. Stay with us and the iconic Green Penguin.

  • 21c Museum Hotel Durham

    Standing tall and proud in the center of downtown Durham, 21c Museum Hotel Durham - MGallery is a multi venue contemporary art museum offering more than 10,500 square feet of art filled exhibition and event space, a full service boutique hotel with luxurious guest rooms, and home to Counting House restaurant.

  • 21c Museum Hotel Lexington

    21c Museum Hotel Lexington - MGallery is an 88 room boutique hotel, contemporary art museum, cultural center and home to Lockbox restaurant, led by executive chef Jonathan Searle. Woven into the fabric of downtown Lexington, 21c welcomes both visitors and the local community to enjoy the curated exhibitions and cultural programming.


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Enjoy exclusive offers with ALL – Accor Live Limitless. Be rewarded during your stay at your preferred destination,** as well as an array of hotels, resorts and private rentals around the world.

*Prices start from, based on a one night stay in a standard double room for two guests. Supplementary services, breakfast and tourist/city tax are not included. Price observed on within the past 24 hours, for a one night stay within the next eight days, starting tomorrow. Price subject to the hotel conditions, period and availability. Depending on the country, these prices may not include taxes, may include VAT only or may include all taxes (VAT and tourist/city tax). When prices do not include all taxes, the relevant taxes (VAT and tourist/city tax) will be stated in the forthcoming stages of the reservation process. The price is only guaranteed at the time of reservation.
**Some hotels in this brand are not participants in the ALL loyalty programme. See the list of non-participating hotels